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Structure paper

TitleConformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry.
Journal, issue, pagesBiochemistry, Vol. 62, Page 2854-2867, Year 2023
Publish dateMay 15, 2023 (structure data deposition date)
AuthorsPallan, P.S. / Lybrand, T.P. / Rozners, E. / Abramov, M. / Schepers, G. / Eremeeva, E. / Herdewijn, P. / Egli, M.
External linksBiochemistry / PubMed:37694722
MethodsX-ray diffraction
Resolution1.51 - 2.3 Å
Structure data

PDB-8sv3:
7-Deazapurines and 5-Halogenpyrimidine DNA duplex
Method: X-RAY DIFFRACTION / Resolution: 1.51 Å

PDB-8sv4:
7-Deazapurines and 5-Halogenpyrimidine DNA duplex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-FWN:
2-[2-(2-ethoxyethoxy)ethoxy]ethanol

ChemComp-ACT:
ACETATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • halalkalibacterium halodurans (bacteria)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN/DNA / 7-Deazapurines / 5-Halogenpyrimidines / Adenine-Tract Geometry / RNase-H complex / DNA duplex / Dickerson-Drew Dodecamer / DNA duplex crystal structure / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex

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