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-Structure paper
Title | Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation. |
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Journal, issue, pages | JCI Insight, Vol. 8, Year 2023 |
Publish date | Dec 1, 2021 (structure data deposition date) |
Authors | Chen, P.Y. / Huang, B.J. / Harris, M. / Boone, C. / Wang, W. / Carias, H. / Mesiona, B. / Mavrici, D. / Kohler, A.C. / Bollag, G. ...Chen, P.Y. / Huang, B.J. / Harris, M. / Boone, C. / Wang, W. / Carias, H. / Mesiona, B. / Mavrici, D. / Kohler, A.C. / Bollag, G. / Zhang, C. / Zhang, Y. / Shannon, K. |
External links | JCI Insight / PubMed:37681415 |
Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | PDB-7t1f: |
Chemicals | ChemComp-GDP: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | ONCOPROTEIN / KRAS / RAS / T50I / KRAS4B / K-RAS |