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-Structure paper
Title | Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate. |
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Journal, issue, pages | Cell Chem Biol, Vol. 30, Page 1402-1413.e7, Year 2023 |
Publish date | Apr 3, 2023 (structure data deposition date) |
![]() | Graboski, A.L. / Kowalewski, M.E. / Simpson, J.B. / Cao, X. / Ha, M. / Zhang, J. / Walton, W.G. / Flaherty, D.P. / Redinbo, M.R. |
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Methods | X-ray diffraction |
Resolution | 1.94 - 2.6 Å |
Structure data | ![]() PDB-8sbg: ![]() PDB-8sij: ![]() PDB-8sl7: |
Chemicals | ![]() ChemComp-PLP: ![]() ChemComp-HOH: ![]() ChemComp-CL: ![]() ChemComp-K9E: ![]() ChemComp-BY3: |
Source |
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![]() | LYASE / PLP-dependent enzyme / tryptophanase / tryptophan-indole lyase / tryptophan indole-lyase / tryptophananse / inhibitor-bound complex |