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Structure paper

TitlePharmacological perturbation of the phase-separating protein SMNDC1.
Journal, issue, pagesNat Commun, Vol. 14, Page 4504-4504, Year 2023
Publish dateJul 4, 2023 (structure data deposition date)
AuthorsEnders, L. / Siklos, M. / Borggrafe, J. / Gaussmann, S. / Koren, A. / Malik, M. / Tomek, T. / Schuster, M. / Reinis, J. / Hahn, E. ...Enders, L. / Siklos, M. / Borggrafe, J. / Gaussmann, S. / Koren, A. / Malik, M. / Tomek, T. / Schuster, M. / Reinis, J. / Hahn, E. / Rukavina, A. / Reicher, A. / Casteels, T. / Bock, C. / Winter, G.E. / Hannich, J.T. / Sattler, M. / Kubicek, S.
External linksNat Commun / PubMed:37587144
MethodsNMR (solution)
Structure data

PDB-8poi:
Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine
Method: SOLUTION NMR

Chemicals

ChemComp-ZTI:
4-pyridin-2-yl-1,3-thiazol-2-amine

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / tudor domain / complex / inhibitor

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