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-Structure paper
Title | Allosteric regulation of switch-II domain controls KRAS oncogenicity. |
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Journal, issue, pages | Cancer Res., Year 2023 |
Publish date | Apr 30, 2020 (structure data deposition date) |
![]() | Yang, M.H. / Tran, T.H. / Hunt, B. / Agnor, R. / Johnson, C.W. / Shui, B. / Waybright, T.J. / Nowak, J.A. / Stephen, A.G. / Simanshu, D.K. / Haigis, K.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.59 - 2.03 Å |
Structure data | ![]() PDB-6ws2: ![]() PDB-6ws4: ![]() PDB-8stm: ![]() PDB-8stn: |
Chemicals | ![]() ChemComp-GDP: ![]() ChemComp-MG: ![]() ChemComp-SO4: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-TCE: ![]() ChemComp-NA: |
Source |
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![]() | ONCOPROTEIN / HYDROLASE / KRAS / RAS / Mg / K-RAS / Small GTPase / Guanine nucleotide / GMPPNP / GppNHp / K104 / G12D / nucleotide-binding protein / signaling protein |