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Structure paper

TitleStructural and molecular insight into antibody recognition of dynamic neoepitopes in membrane tethered MUC1 of pancreatic cancer cells and secreted exosomes.
Journal, issue, pagesRsc Chem Biol, Vol. 4, Page 564-572, Year 2023
Publish dateDec 15, 2022 (structure data deposition date)
AuthorsWakui, H. / Yokoi, Y. / Horidome, C. / Ose, T. / Yao, M. / Tanaka, Y. / Hinou, H. / Nishimura, S.I.
External linksRsc Chem Biol / PubMed:37547453
MethodsX-ray diffraction
Resolution2.07 Å
Structure data

PDB-8hrh:
SN-131/1B2 anti-MUC1 antibody with a glycopeptide
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-N7P:
1-ACETYL-L-PROLINE

ChemComp-ASP:
ASPARTIC ACID

ChemComp-THR:
THREONINE

ChemComp-ARG:
ARGININE

ChemComp-ALA:
ALANINE

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-PRO:
PROLINE

ChemComp-LPD:
L-PROLINAMIDE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / antibody

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