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-Structure paper
Title | A novel Toll-like receptor 7/8-specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus. |
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Journal, issue, pages | Eur. J. Pharmacol., Vol. 957, Page 175962-175962, Year 2023 |
Publish date | Aug 16, 2022 (structure data deposition date) |
Authors | Ishizaka, S.T. / Hawkins, L. / Chen, Q. / Tago, F. / Yagi, T. / Sakaniwa, K. / Zhang, Z. / Shimizu, T. / Shirato, M. |
External links | Eur. J. Pharmacol. / PubMed:37544422 |
Methods | X-ray diffraction |
Resolution | 2.9 Å |
Structure data | PDB-7ytx: |
Chemicals | ChemComp-JRI: ChemComp-NAG: |
Source |
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Keywords | IMMUNE SYSTEM / Toll-like receptor 8 / inhibitor |