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TitlePermissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by gamma-Secretase.
Journal, issue, pagesJ. Mol. Biol., Vol. 435, Page 168218-168218, Year 2023
Publish dateApr 13, 2023 (structure data deposition date)
AuthorsOrtner, M. / Guschtschin-Schmidt, N. / Stelzer, W. / Muhle-Goll, C. / Langosch, D.
External linksJ. Mol. Biol. / PubMed:37536392
MethodsNMR (solution)
Structure data

PDB-8or5:
Solution NMR structure of Notch1 TMD
Method: SOLUTION NMR

PDB-8ory:
Solution NMR structure of Notch1 L1740-1743 TMD
Method: SOLUTION NMR

PDB-8orz:
Solution NMR structure of Notch1 G1740-1743 TMD
Method: SOLUTION NMR

PDB-8os0:
Solution NMR structure of Notch3 WT TMD
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Notch1 / gamma secretase / transmembrane / Notch1 L1740-1743 / Notch1 G1740-1743 / Notch3 WT

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