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Structure paper

TitlePractical Synthesis of N -Formylmethionylated Peptidyl-tRNA Mimics.
Journal, issue, pagesAcs Chem. Biol., Vol. 18, Page 2233-2239, Year 2023
Publish dateJun 22, 2023 (structure data deposition date)
AuthorsThaler, J. / Syroegin, E.A. / Breuker, K. / Polikanov, Y.S. / Micura, R.
External linksAcs Chem. Biol. / PubMed:37433044
MethodsX-ray diffraction
Resolution2.6 - 2.65 Å
Structure data

PDB-8t8b:
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MAI-tripeptidyl-tRNA analog ACCA-IAMf at 2.65A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-8t8c:
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MFI-tripeptidyl-tRNA analog ACCA-IFMf at 2.60A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-ARG:
ARGININE

ChemComp-ZN:
Unknown entry

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-HOH:
WATER

Source
  • escherichia coli k-12 (bacteria)
  • thermus thermophilus hb8 (bacteria)
  • escherichia coli (E. coli)
KeywordsRIBOSOME/RNA / 70S ribosome / peptidyl-tRNA / RNA-peptide conjugate / RNA modification / FT-ICR mass spectrometry / formylation / RIBOSOME / RIBOSOME-RNA complex

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