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TitleA novel single alpha-helix DNA-binding domain in CAF-1 promotes gene silencing and DNA damage survival through tetrasome-length DNA selectivity and spacer function.
Journal, issue, pagesElife, Vol. 12, Year 2023
Publish dateJun 20, 2022 (structure data deposition date)
AuthorsRosas, R. / Aguilar, R.R. / Arslanovic, N. / Seck, A. / Smith, D.J. / Tyler, J.K. / Churchill, M.E.A.
External linksElife / PubMed:37432722
MethodsX-ray diffraction
Resolution2.81 Å
Structure data

PDB-8dei:
Structure of the Cac1 KER domain
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsDNA BINDING PROTEIN / chromatin / DNA binding

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