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Structure paper

TitleStructural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Journal, issue, pagesAntiviral Res., Vol. 216, Page 105663-105663, Year 2023
Publish dateMar 23, 2023 (structure data deposition date)
AuthorsSkvara, P. / Chalupska, D. / Klima, M. / Kozic, J. / Silhan, J. / Boura, E.
External linksAntiviral Res. / PubMed:37421984
MethodsX-ray diffraction
Resolution2.12 Å
Structure data

PDB-8oiv:
Monkeypox virus VP39 in complex with SAH and cap0
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-GTG:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

ChemComp-HOH:
WATER

Source
  • monkeypox virus
  • synthetic construct (others)
KeywordsTRANSFERASE / Methyltransferase / Ligand / Monkeypox virus

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