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TitleHuman cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate.
Journal, issue, pagesJ. Biol. Chem., Vol. 299, Page 104993-104993, Year 2023
Publish dateMar 16, 2023 (structure data deposition date)
AuthorsLiu, J. / Kandel, S.E. / Lampe, J.N. / Scott, E.E.
External linksJ. Biol. Chem. / PubMed:37392852
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-8gk3:
Cytochrome P450 3A7 in complex with Dehydroepiandrosterone sulfate
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-ZWY:
17-oxoandrost-5-en-3beta-yl hydrogen sulfate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / Monooxygenase

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