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-Structure paper
Title | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. |
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Journal, issue, pages | Mol Neurodegener, Vol. 18, Page 38-38, Year 2023 |
Publish date | Aug 31, 2022 (structure data deposition date) |
![]() | Nemergut, M. / Marques, S.M. / Uhrik, L. / Vanova, T. / Nezvedova, M. / Gadara, D.C. / Jha, D. / Tulis, J. / Novakova, V. / Planas-Iglesias, J. ...Nemergut, M. / Marques, S.M. / Uhrik, L. / Vanova, T. / Nezvedova, M. / Gadara, D.C. / Jha, D. / Tulis, J. / Novakova, V. / Planas-Iglesias, J. / Kunka, A. / Legrand, A. / Hribkova, H. / Pospisilova, V. / Sedmik, J. / Raska, J. / Prokop, Z. / Damborsky, J. / Bohaciakova, D. / Spacil, Z. / Hernychova, L. / Bednar, D. / Marek, M. |
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Methods | X-ray diffraction |
Resolution | 1.549 - 1.9 Å |
Structure data | ![]() PDB-8ax8: ![]() PDB-8ax9: ![]() PDB-8cdy: ![]() PDB-8ce0: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-GOL: |
Source |
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![]() | LIPID BINDING PROTEIN / Apolipoprotein E / LIPID TRANSPORT / N-terminal domain |