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-Structure paper
Title | Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 91, Page 129352-129352, Year 2023 |
Publish date | Nov 1, 2022 (structure data deposition date) |
![]() | Grimster, N.P. / Gingipalli, L. / Balazs, A. / Barlaam, B. / Boiko, S. / Boyd, S. / Dry, H. / Goldberg, F.W. / Ikeda, T. / Johnson, T. ...Grimster, N.P. / Gingipalli, L. / Balazs, A. / Barlaam, B. / Boiko, S. / Boyd, S. / Dry, H. / Goldberg, F.W. / Ikeda, T. / Johnson, T. / Kawatkar, S. / Kemmitt, P. / Lamont, S. / Lorthioir, O. / Mfuh, A. / Patel, J. / Pike, A. / Read, J. / Romero, R. / Sarkar, U. / Sha, L. / Simpson, I. / Song, K. / Su, Q. / Wang, H. / Watson, D. / Wu, A. / Zehnder, T.E. / Zheng, X. / Li, S. / Dong, Z. / Yang, D. / Song, Y. / Wang, P. / Liu, X. / Dowling, J.E. / Edmondson, S.D. |
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Methods | X-ray diffraction |
Resolution | 1.508 Å |
Structure data | ![]() PDB-8bi2: |
Chemicals | ![]() ChemComp-QR7: ![]() ChemComp-HOH: |
Source |
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