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-Structure paper
| Title | Reduced dynamic complexity allows structure elucidation of an excited state of KRAS G13D . |
|---|---|
| Journal, issue, pages | Commun Biol, Vol. 6, Page 594-594, Year 2023 |
| Publish date | Aug 31, 2022 (structure data deposition date) |
Authors | Chao, F.A. / Chan, A.H. / Dharmaiah, S. / Schwieters, C.D. / Tran, T.H. / Taylor, T. / Ramakrishnan, N. / Esposito, D. / Nissley, D.V. / McCormick, F. ...Chao, F.A. / Chan, A.H. / Dharmaiah, S. / Schwieters, C.D. / Tran, T.H. / Taylor, T. / Ramakrishnan, N. / Esposito, D. / Nissley, D.V. / McCormick, F. / Simanshu, D.K. / Cornilescu, G. |
External links | Commun Biol / PubMed:37268708 |
| Methods | X-ray diffraction |
| Resolution | 1.2 - 2 Å |
| Structure data | ![]() PDB-8ebz: ![]() PDB-8epw: |
| Chemicals | ![]() ChemComp-GNP: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
| Source |
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Keywords | ONCOPROTEIN / KRAS / K-RAS / mutant / cancer / RAS / small GTPase / GMPPNP / GppNHp / G13D / hydrolase / KRAS4b / RAF1 / CRAF / RBD / RAS-binding domain |
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