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-Structure paper
Title | Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-alpha-amino acids in vitro and in vivo. |
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Journal, issue, pages | Nat. Chem., Vol. 15, Page 960-971, Year 2023 |
Publish date | Feb 18, 2022 (structure data deposition date) |
Authors | Fricke, R. / Swenson, C.V. / Roe, L.T. / Hamlish, N.X. / Shah, B. / Zhang, Z. / Ficaretta, E. / Ad, O. / Smaga, S. / Gee, C.L. ...Fricke, R. / Swenson, C.V. / Roe, L.T. / Hamlish, N.X. / Shah, B. / Zhang, Z. / Ficaretta, E. / Ad, O. / Smaga, S. / Gee, C.L. / Chatterjee, A. / Schepartz, A. |
External links | Nat. Chem. / PubMed:37264106 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-7u0r: |
Chemicals | ChemComp-LE0: ChemComp-ANP: ChemComp-TRS: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | TRANSLATION/INHIBITOR / aminoacyl-tRNA synthetase / ligase / non-natural amino acids / pyrrolysyl-tRNA synthetase / TRANSLATION / TRANSLATION-INHIBITOR complex |