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TitleSemisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3.
Journal, issue, pagesAcs Cent. Sci., Vol. 9, Page 1025-1034, Year 2023
Publish dateJul 18, 2022 (structure data deposition date)
AuthorsFarnung, J. / Muhar, M. / Liang, J.R. / Tolmachova, K.A. / Benoit, R.M. / Corn, J.E. / Bode, J.W.
External linksAcs Cent. Sci. / PubMed:37252361
MethodsX-ray diffraction
Resolution2.66 Å
Structure data

PDB-8afi:
GABARAP in complex with LIR motif of HsATG3
Method: X-RAY DIFFRACTION / Resolution: 2.66 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Autophagy / LIR / ATG3 / GABARAP

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