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TitleA blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders.
Journal, issue, pagesNat Commun, Vol. 14, Page 2960-2960, Year 2023
Publish dateAug 10, 2022 (structure data deposition date)
AuthorsKatagiri, T. / Tsukamoto, S. / Kuratani, M. / Tsuji, S. / Nakamura, K. / Ohte, S. / Kawaguchi, Y. / Takaishi, K.
External linksNat Commun / PubMed:37231012
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-7yru:
ALK2 antibody complex
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE/IMMUNE SYSTEM / ALK2 / PROTEIN BINDING / TRANSFERASE-IMMUNE SYSTEM complex / IMMUNE SYSTEM

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