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Structure paper

TitleThe oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum.
Journal, issue, pagesJ. Steroid Biochem. Mol. Biol., Vol. 231, Page 106317-106317, Year 2023
Publish dateMar 6, 2023 (structure data deposition date)
AuthorsGhith, A. / Bruning, J.B. / Bell, S.G.
External linksJ. Steroid Biochem. Mol. Biol. / PubMed:37141947
MethodsX-ray diffraction
Resolution1.81 Å
Structure data

PDB-8gdi:
X-ray crystal structure of CYP124A1 from Mycobacterium Marinum in complex with 7-ketocholesterol
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-0GV:
(3beta,8alpha,9beta)-3-hydroxycholest-5-en-7-one

ChemComp-HOH:
WATER

Source
  • mycobacterium marinum (bacteria)
KeywordsOXIDOREDUCTASE / Cytochrome P450 / ligand bound

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