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TitleAn African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Journal, issue, pagesCancer Discov, Vol. 13, Page 1696-1719, Year 2023
Publish dateAug 23, 2022 (structure data deposition date)
AuthorsIndeglia, A. / Leung, J.C. / Miller, S.A. / Leu, J.I. / Dougherty, J.F. / Clarke, N.L. / Kirven, N.A. / Shao, C. / Ke, L. / Lovell, S. ...Indeglia, A. / Leung, J.C. / Miller, S.A. / Leu, J.I. / Dougherty, J.F. / Clarke, N.L. / Kirven, N.A. / Shao, C. / Ke, L. / Lovell, S. / Barnoud, T. / Lu, D.Y. / Lin, C. / Kannan, T. / Battaile, K.P. / Yang, T.H.L. / Batista Oliva, I. / Claiborne, D.T. / Vogel, P. / Liu, L. / Liu, Q. / Nefedova, Y. / Cassel, J. / Auslander, N. / Kossenkov, A.V. / Karanicolas, J. / Murphy, M.E.
External linksCancer Discov / PubMed:37140445
MethodsX-ray diffraction
Resolution1.3 - 2.5 Å
Structure data

PDB-8e7a:
Crystal structure of the p53 (Y107H) core domain orthorhombic P form
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-8e7b:
Crystal structure of the p53 (Y107H) core domain monoclinic P form
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN

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