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TitleDual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
Journal, issue, pagesPlos Pathog., Vol. 19, Page e1011373-e1011373, Year 2023
Publish dateDec 20, 2022 (structure data deposition date)
AuthorsFerrer-Orta, C. / Ferrero, D.S. / Verdaguer, N.
External linksPlos Pathog. / PubMed:37126532
MethodsX-ray diffraction
Resolution1.7 - 1.85 Å
Structure data

PDB-8c1n:
FMDV 3D polymerase in complex with 3B1 protein solved in P212121 space group
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-8c2p:
FMDV 3D polymerase in complex with 3B3
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-3PO:
TRIPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • foot-and-mouth disease virus
KeywordsVIRAL PROTEIN / RNA dependent RNA polymerase FMDV Picornavirus 3B VPg

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