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Structure paper

TitlePK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties.
Journal, issue, pagesOpen Biology, Vol. 13, Page 220350-220350, Year 2023
Publish dateJul 29, 2022 (structure data deposition date)
AuthorsZacharchenko, T. / Dorendorf, T. / Locker, N. / Van Dijk, E. / Katzemich, A. / Diederichs, K. / Bullard, B. / Mayans, O.
External linksOpen Biology / PubMed:37121260
MethodsX-ray diffraction
Resolution1.75 - 1.9 Å
Structure data

PDB-8ak2:
Drosophila melanogaster UNC89 Protein Kinase Domain 1 (apo)
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-8ak3:
Drosophila melanogaster UNC89 Protein Kinase 1 in complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • drosophila melanogaster (fruit fly)
KeywordsSTRUCTURAL PROTEIN / Kinase / Muscle Protein / ATP-binding

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