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Structure paper

TitleStructural insights into thrombolytic activity of destabilase from medicinal leech.
Journal, issue, pagesSci Rep, Vol. 13, Page 6641-6641, Year 2023
Publish dateOct 14, 2022 (structure data deposition date)
AuthorsMarin, E. / Kornilov, D.A. / Bukhdruker, S.S. / Aleksenko, V.A. / Manuvera, V.A. / Zinovev, E.V. / Kovalev, K.V. / Shevtsov, M.B. / Talyzina, A.A. / Bobrovsky, P.A. ...Marin, E. / Kornilov, D.A. / Bukhdruker, S.S. / Aleksenko, V.A. / Manuvera, V.A. / Zinovev, E.V. / Kovalev, K.V. / Shevtsov, M.B. / Talyzina, A.A. / Bobrovsky, P.A. / Kuzmichev, P.K. / Mishin, A.V. / Gushchin, I.Y. / Lazarev, V.N. / Borshchevskiy, V.I.
External linksSci Rep / PubMed:37095116
MethodsX-ray diffraction
Resolution1.1 - 1.4 Å
Structure data

PDB-8bbu:
Crystal structure of medical leech destabilase (high salt)
Method: X-RAY DIFFRACTION / Resolution: 1.1 Å

PDB-8bbw:
Crystal structure of medical leech destabilase (low salt)
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-MLI:
MALONATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • hirudo medicinalis (medicinal leech)
KeywordsHYDROLASE / lysozyme / muramidase / isopeptidase / glycosidase / antibacterial

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