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-Structure paper
Title | The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 67, Page e0156322-e0156322, Year 2023 |
Publish date | Mar 21, 2022 (structure data deposition date) |
Authors | Mason, C.S. / Avis, T. / Hu, C. / Nagalingam, N. / Mudaliar, M. / Coward, C. / Begum, K. / Gajewski, K. / Alam, M.J. / Basseres, E. ...Mason, C.S. / Avis, T. / Hu, C. / Nagalingam, N. / Mudaliar, M. / Coward, C. / Begum, K. / Gajewski, K. / Alam, M.J. / Basseres, E. / Moss, S. / Reich, S. / Duperchy, E. / Fox, K.R. / Garey, K.W. / Powell, D.J. |
External links | Antimicrob. Agents Chemother. / PubMed:37093023 |
Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | PDB-7z9p: |
Chemicals | ChemComp-IK7: ChemComp-SO4: ChemComp-NA: ChemComp-ZN: ChemComp-HOH: |
Source |
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Keywords | DNA / Clostridiodes difficile / antibiotic / DNA-binding / drug discovery / target identification |