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TitleIn vitro antifungal and antibiofilm activities of auranofin against itraconazole-resistant Aspergillus fumigatus.
Journal, issue, pagesJ Mycol Med, Vol. 33, Page 101381-101381, Year 2023
Publish dateAug 16, 2022 (structure data deposition date)
AuthorsChen, P. / Yang, J. / Jin, Y. / Lu, C. / Feng, Z. / Gao, F. / Chen, Y. / Wang, F. / Shang, Z. / Lin, W.
External linksJ Mycol Med / PubMed:37037064
MethodsX-ray diffraction
Resolution3.866 Å
Structure data

PDB-7ytv:
Crystal structure of Aspergillus fumigatus Thioredoxin reductase in complex with auranofin
Method: X-RAY DIFFRACTION / Resolution: 3.866 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-HOH:
WATER

Source
  • aspergillus fumigatus (mold)
KeywordsOXIDOREDUCTASE / Thioredoxin reductase / reductase / auranofin

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