+Search query
-Structure paper
Title | Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 66, Page 5703-5718, Year 2023 |
Publish date | Feb 25, 2023 (structure data deposition date) |
Authors | Ivanova, J.N. / Nocentini, A. / Tars, K. / Leita Ns, J.N. / Dvinskis, E. / Kazaks, A. / Domraceva, I. / Supuran, C.T. / Zalubovskis, R. |
External links | J. Med. Chem. / PubMed:37022308 |
Methods | X-ray diffraction |
Resolution | 1.68 - 2.3 Å |
Structure data | PDB-8co0: PDB-8co3: |
Chemicals | ChemComp-ZN: ChemComp-V8O: ChemComp-GOL: ChemComp-HOH: |
Source |
|
Keywords | LYASE / CA IX / CA 9 / carbonic anhydrase IX / carbonic anhydrase 9 / CA XII / CA 12 / carbonic anhydrase XII / carbonic anhydrase 12 |