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TitleDiverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties.
Journal, issue, pagesSci Transl Med, Vol. 15, Page eabn9155-eabn9155, Year 2023
Publish dateAug 24, 2021 (structure data deposition date)
AuthorsSong, H. / Wu, J. / Tang, Y. / Dai, Y. / Xiang, X. / Li, Y. / Wu, L. / Liang, Y. / Xing, Y. / Yan, N. ...Song, H. / Wu, J. / Tang, Y. / Dai, Y. / Xiang, X. / Li, Y. / Wu, L. / Liang, Y. / Xing, Y. / Yan, N. / Wang, Z. / Xiao, S. / Li, J. / Zheng, D. / Chen, X. / Fang, H. / Ye, C. / Ma, Y. / Wu, Y. / Wu, W. / Zhang, S. / Lu, M.
External linksSci Transl Med / PubMed:37018419
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-7v97:
Arsenic-bound p53 DNA-binding domain mutant V272M
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-ARS:
ARSENIC

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Keywords: DNA-binding domain / complex / DNA-bound / Arsenic-bound

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