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Structure paper

TitleMolecular basis for METTL9-mediated N1-histidine methylation.
Journal, issue, pagesCell Discov, Vol. 9, Page 38-38, Year 2023
Publish dateJun 24, 2022 (structure data deposition date)
AuthorsWang, X. / Xie, H. / Guo, Q. / Cao, D. / Ru, W. / Zhao, S. / Zhu, Z. / Zhang, J. / Pan, W. / Yao, X. / Xu, C.
External linksCell Discov / PubMed:37015930
MethodsX-ray diffraction
Resolution1.691 - 3.434 Å
Structure data

PDB-7y9c:
Crystal structure of METTL9 in complex with SLC39A5 peptide and SAH
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-7yf2:
Crystal structure of METTL9 in complex with unmethylated SLC39A5 peptide and SAH
Method: X-RAY DIFFRACTION / Resolution: 1.691 Å

PDB-7yf3:
Crystal structure of METTL9 in complex with unmethylated S100A9 peptide and SAH
Method: X-RAY DIFFRACTION / Resolution: 3.434 Å

PDB-7yf4:
Crystal structure of METTL9 in complex with SLC39A5 mutant peptide and SAH
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
  • mus musculus (house mouse)
KeywordsTRANSFERASE / METTL9 / SLC39A5 / histidine methyltransferase / S100A9

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