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TitleA DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 120, Page e2300150120-e2300150120, Year 2023
Publish dateSep 20, 2022 (structure data deposition date)
AuthorsYates, L.A. / Tannous, E.A. / Morgan, R.M. / Burgers, P.M. / Zhang, X.
External linksProc. Natl. Acad. Sci. USA / PubMed:36996117
MethodsX-ray diffraction
Resolution1.55 - 1.58 Å
Structure data

PDB-8b4j:
Rfa1-N-terminal domain in complex with phosphorylated Ddc2
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

PDB-8b4k:
Rfa1-N-terminal domain in complex with phosphorylated Ddc2
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsPROTEIN BINDING / Complex / OB-fold / Replication Protein A / DNA damage response / Replication

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