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| Title | Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors. |
|---|---|
| Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 62, Page e202301258-e202301258, Year 2023 |
| Publish date | May 8, 2022 (structure data deposition date) |
Authors | Danby, P.M. / Jeong, A. / Sim, L. / Sweeney, R.P. / Wardman, J.F. / Karimi, R. / Geissner, A. / Worrall, L.J. / Reid, J.P. / Strynadka, N.C.J. / Withers, S.G. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:36940280 |
| Methods | X-ray diffraction |
| Resolution | 1.58 - 1.83 Å |
| Structure data | ![]() PDB-7uz1: ![]() PDB-7uz2: |
| Chemicals | ![]() ChemComp-OM0: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-OML: |
| Source |
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Keywords | HYDROLASE / Covalent Inhibition / Glycoside Hydrolase |
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saccharolobus solfataricus (archaea)
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