Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants.
Journal, issue, pages	Signal Transduct Target Ther, Vol. 8, Page 128-128, Year 2023
Publish date	Nov 17, 2022 (structure data deposition date)
Authors	Huang, C. / Shuai, H. / Qiao, J. / Hou, Y. / Zeng, R. / Xia, A. / Xie, L. / Fang, Z. / Li, Y. / Yoon, C. ...Huang, C. / Shuai, H. / Qiao, J. / Hou, Y. / Zeng, R. / Xia, A. / Xie, L. / Fang, Z. / Li, Y. / Yoon, C. / Huang, Q. / Hu, B. / You, J. / Quan, B. / Zhao, X. / Guo, N. / Zhang, S. / Ma, R. / Zhang, J. / Wang, Y. / Yang, R. / Nan, J. / Xu, H. / Wang, F. / Lei, J. / Chu, H. / Yang, S.
External links	Signal Transduct Target Ther / PubMed:36928316
Methods	X-ray diffraction
Resolution	1.95 - 2.258 Å
Structure data	PDB-8hht: Crystal structure of the SARS-CoV-2 main protease in complex with Hit-1 Method: X-RAY DIFFRACTION / Resolution: 1.95 Å PDB-8hhu: Crystal structure of the SARS-CoV-2 main protease in complex with SY110 Method: X-RAY DIFFRACTION / Resolution: 2.258 Å
Chemicals	ChemComp-LV0: ~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]benzamide ChemComp-DMS: DIMETHYL SULFOXIDE / DMSO, precipitantYM ChemComp-HOH: WATER ChemComp-LVX*: (1~{R})-3,3-bis(fluoranyl)-~{N}-[(2~{R})-3-methoxy-1-oxidanylidene-1-[[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]amino]propan-2-yl]cyclohexane-1-carboxamide
Source	severe acute respiratory syndrome coronavirus 2
Keywords	VIRAL PROTEIN / Severe acute respiratory syndrome coronavirus 2 / main protease