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TitleMolecular determinants for differential activation of the bile acid receptor from the pathogen Vibrio parahaemolyticus.
Journal, issue, pagesJ. Biol. Chem., Vol. 299, Page 104591-104591, Year 2023
Publish dateJul 8, 2022 (structure data deposition date)
AuthorsZou, A.J. / Kinch, L. / Chimalapati, S. / Garcia, N. / Tomchick, D.R. / Orth, K.
External linksJ. Biol. Chem. / PubMed:36894018
MethodsX-ray diffraction
Resolution2.08 Å
Structure data

PDB-8dml:
Vibrio parahaemolyticus VtrA/VtrC complex bound to the bile salt chenodeoxycholate
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-JN3:
CHENODEOXYCHOLIC ACID

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • vibrio parahaemolyticus (bacteria)
KeywordsSIGNALING PROTEIN / heterodimer / alpha/beta / calycin beta barrel superfamily / bile salt receptor / chenodeoxycholate

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