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-Structure paper
Title | Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 18, Page 772-784, Year 2023 |
Publish date | Jul 29, 2022 (structure data deposition date) |
Authors | Thakur, A.K. / Miller, S.E. / Liau, N.P.D. / Hwang, S. / Hansen, S. / de Sousa E Melo, F. / Sudhamsu, J. / Hannoush, R.N. |
External links | Acs Chem. Biol. / PubMed:36893429 |
Methods | X-ray diffraction |
Resolution | 2 - 2.53 Å |
Structure data | PDB-8dvl: PDB-8dvm: PDB-8dvn: |
Chemicals | ChemComp-NAG: ChemComp-CA: ChemComp-EDO: ChemComp-HOH: ChemComp-MES: |
Source |
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Keywords | SIGNALING PROTEIN / LRP6 / E3E4 / Wnt Signaling / Disulfide constrained peptide / Wnt agonism |