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-Structure paper
Title | Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice. |
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Journal, issue, pages | JHEP Rep, Vol. 5, Page 100651-100651, Year 2023 |
Publish date | Jun 10, 2022 (structure data deposition date) |
![]() | Seedorf, K. / Weber, C. / Vinson, C. / Berger, S. / Vuillard, L.M. / Kiss, A. / Creusot, S. / Broux, O. / Geant, A. / Ilic, C. ...Seedorf, K. / Weber, C. / Vinson, C. / Berger, S. / Vuillard, L.M. / Kiss, A. / Creusot, S. / Broux, O. / Geant, A. / Ilic, C. / Lemaitre, K. / Richard, J. / Hammoutene, A. / Mahieux, J. / Martiny, V. / Durand, D. / Melchiore, F. / Nyerges, M. / Paradis, V. / Provost, N. / Duvivier, V. / Delerive, P. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.323 Å |
Structure data | ![]() PDB-8a46: |
Chemicals | ![]() ChemComp-L5F: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / master regulator of cellular resistance to oxidants |