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TitlePathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage.
Journal, issue, pagesAnn Rheum Dis, Vol. 82, Page 799-808, Year 2023
Publish dateOct 13, 2022 (structure data deposition date)
AuthorsLi, T. / Ge, C. / Kramer, A. / Sareila, O. / Leu Agelii, M. / Johansson, L. / Forslind, K. / Lonnblom, E. / Yang, M. / Xu, B. ...Li, T. / Ge, C. / Kramer, A. / Sareila, O. / Leu Agelii, M. / Johansson, L. / Forslind, K. / Lonnblom, E. / Yang, M. / Xu, B. / Li, Q. / Cheng, L. / Bergstrom, G. / Fernandez, G. / Kastbom, A. / Rantapaa-Dahlqvist, S. / Gjertsson, I. / Holmdahl, R.
External linksAnn Rheum Dis / PubMed:36858822
MethodsX-ray diffraction
Resolution1.619 Å
Structure data

PDB-8bbh:
The crystal structure of a mouse Fab fragment TL1 in complex with a human Glucose-6-phosphate isomerase peptide 293-307
Method: X-RAY DIFFRACTION / Resolution: 1.619 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antibody Fab fragment

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