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-Structure paper
Title | Structural and Antibacterial Characterization of a New Benzamide FtsZ Inhibitor with Superior Bactericidal Activity and In Vivo Efficacy Against Multidrug-Resistant Staphylococcus aureus. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 18, Page 629-642, Year 2023 |
Publish date | Dec 21, 2022 (structure data deposition date) |
Authors | Bryan, E. / Ferrer-Gonzalez, E. / Sagong, H.Y. / Fujita, J. / Mark, L. / Kaul, M. / LaVoie, E.J. / Matsumura, H. / Pilch, D.S. |
External links | Acs Chem. Biol. / PubMed:36854145 |
Methods | X-ray diffraction |
Resolution | 1.3 Å |
Structure data | PDB-8htb: |
Chemicals | ChemComp-GDP: ChemComp-CA: ChemComp-ZI9: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / GTPase / protein-inhibitor complex / antibacterial agent |