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Structure paper

TitleStructure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies.
Journal, issue, pagesJ. Biol. Chem., Vol. 299, Page 103062-103062, Year 2023
Publish dateNov 9, 2022 (structure data deposition date)
AuthorsBruun, T.U.J. / Tang, S. / Erwin, G. / Deis, L. / Fernandez, D. / Kim, P.S.
External linksJ. Biol. Chem. / PubMed:36841484
MethodsX-ray diffraction
Resolution1.2 - 2 Å
Structure data

PDB-8f3a:
HIV-1 gp41 coiled-coil pocket IQN17
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-8f3b:
HIV-1 gp41 coiled-coil pocket IQN22
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ACY:
ACETIC ACID

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • hiv-1 m:b_hxb2r (virus)
KeywordsVIRAL PROTEIN / HIV-1 / gp41 / coiled-coil / pocket

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