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-Structure paper
Title | Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. |
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Journal, issue, pages | Chem. Commun. (Camb. ), Vol. 59, Page 3126-3129, Year 2023 |
Publish date | Aug 4, 2022 (structure data deposition date) |
Authors | Dickmann, C.G.F. / McDonald, A.F. / Huynh, N. / Rigopoulos, A. / Liu, Z. / Guo, N. / Osellame, L.D. / Gorman, M.A. / Parker, M.W. / Gan, H.K. ...Dickmann, C.G.F. / McDonald, A.F. / Huynh, N. / Rigopoulos, A. / Liu, Z. / Guo, N. / Osellame, L.D. / Gorman, M.A. / Parker, M.W. / Gan, H.K. / Scott, A.M. / Ackermann, U. / Burvenich, I.J.G. / White, J.M. |
External links | Chem. Commun. (Camb. ) / PubMed:36809538 |
Methods | X-ray diffraction |
Resolution | 1.47 Å |
Structure data | PDB-8dyr: PDB-8e17: PDB-8e3w: |
Chemicals | ChemComp-U59: ChemComp-EDO: ChemComp-HOH: ChemComp-U7R: ChemComp-UHI: |
Source |
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Keywords | GENE REGULATION / bromodomain / BET inhibitor / BRD4 / PET radiotracer / solid tumor imaging / GENE REGULATION/INHIBITOR / GENE REGULATION-INHIBITOR complex |