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Structure paper

TitleStructural and Functional Characterization of Mycobacterium tuberculosis Homoserine Transacetylase.
Journal, issue, pagesAcs Infect Dis., Vol. 9, Page 540-553, Year 2023
Publish dateAug 26, 2021 (structure data deposition date)
AuthorsSharma, S. / Jayasinghe, Y.P. / Mishra, N.K. / Orimoloye, M.O. / Wong, T.Y. / Dalluge, J.J. / Ronning, D.R. / Aldrich, C.C.
External linksAcs Infect Dis. / PubMed:36753622
MethodsX-ray diffraction
Resolution2.67 - 2.89 Å
Structure data

PDB-7ryt:
Crystal structure of Mycobacterium tuberculosis acetylated Homoserine transacetylase with Coenzyme A
Method: X-RAY DIFFRACTION / Resolution: 2.67 Å

PDB-8f2l:
Crystal structure of Mycobacterium tuberculosis Homoserine transacetylase in complex with L-Homoserine
Method: X-RAY DIFFRACTION / Resolution: 2.89 Å

Chemicals

ChemComp-COA:
COENZYME A

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-HSE:
L-HOMOSERINE

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTRANSFERASE / Alpha beta hydrolase / acetylated / acetyl tansferase / PROTEIN BINDING / L-homoserine / acetyl transferase / Methionine biosynthesis

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