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TitleA small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 120, Page e2213670120-e2213670120, Year 2023
Publish dateJun 18, 2022 (structure data deposition date)
AuthorsLin, Y. / Shi, Q. / Yang, G. / Shi, F. / Zhou, Y. / Wang, T. / Xu, P. / Li, P. / Liu, Z. / Sun, H. ...Lin, Y. / Shi, Q. / Yang, G. / Shi, F. / Zhou, Y. / Wang, T. / Xu, P. / Li, P. / Liu, Z. / Sun, H. / Zhao, Z. / Ding, K. / Wang, Z. / Feng, H. / Yu, B. / Fang, P. / Wang, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:36749723
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-7y62:
Crystal structure of human TFEB HLHLZ domain
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / TRANSCRIPTION FACTOR

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