Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors.
Journal, issue, pages	J. Med. Chem., Vol. 66, Page 2386-2395, Year 2023
Publish date	May 19, 2022 (structure data deposition date)
Authors	Blum, A. / Dorsch, D. / Linde, N. / Brandstetter, S. / Buchstaller, H.P. / Busch, M. / Glaser, N. / Gradler, U. / Ruff, A. / Petersson, C. ...Blum, A. / Dorsch, D. / Linde, N. / Brandstetter, S. / Buchstaller, H.P. / Busch, M. / Glaser, N. / Gradler, U. / Ruff, A. / Petersson, C. / Schieferstein, H. / Sherbetjian, E. / Esdar, C.
External links	J. Med. Chem. / PubMed:36728508
Methods	X-ray diffraction
Resolution	2.119 - 3.09 Å
Structure data	PDB-7zw8: Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST Method: X-RAY DIFFRACTION / Resolution: 2.119 Å PDB-7zy6: Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST Method: X-RAY DIFFRACTION / Resolution: 3.09 Å
Chemicals	ChemComp-K3R: ~{N}-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine ChemComp-HOH: WATER ChemComp-KCI: 5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-3-yl)ethyl]pyridin-3-amine
Source	homo sapiens (human)
Keywords	TRANSFERASE / TYROSINE-PROTEIN KINASE / cKIT