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TitleFunctional Impact of a Cancer-Related Variant in Human Delta 1 -Pyrroline-5-Carboxylate Reductase 1.
Journal, issue, pagesAcs Omega, Vol. 8, Page 3509-3519, Year 2023
Publish dateJul 5, 2022 (structure data deposition date)
AuthorsDaudu, O.I. / Meeks, K.R. / Zhang, L. / Seravalli, J. / Tanner, J.J. / Becker, D.F.
External linksAcs Omega / PubMed:36713721
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-8dkg:
Structure of PYCR1 Thr171Met variant complexed with NADH
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / AMINO-ACID BIOSYNTHESIS / PROLINE BIOSYNTHESIS

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