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-Structure paper
Title | A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy. |
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Journal, issue, pages | Plos Pathog., Vol. 19, Page e1011085-e1011085, Year 2023 |
Publish date | Jan 26, 2022 (structure data deposition date) |
Authors | Meng, L. / Zha, J. / Zhou, B. / Cao, L. / Jiang, C. / Zhu, Y. / Li, T. / Lu, L. / Zhang, J. / Yang, H. ...Meng, L. / Zha, J. / Zhou, B. / Cao, L. / Jiang, C. / Zhu, Y. / Li, T. / Lu, L. / Zhang, J. / Yang, H. / Feng, J. / Gu, Z. / Tang, H. / Jiang, L. / Li, D. / Lavillette, D. / Zhang, X. |
External links | Plos Pathog. / PubMed:36706160 |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | PDB-7wqv: |
Chemicals | ChemComp-MPD: ChemComp-CA: ChemComp-CL: ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN / Ab08 / mAb / Coronavirus / Covid-19 / Monoclonal antibody / nAb / Neutralizing antibody / RBD / Receptor-binding domain / SARS-CoV-2 |