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TitleA novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Journal, issue, pagesAntib Ther, Vol. 6, Page 1-12, Year 2023
Publish dateJun 21, 2022 (structure data deposition date)
AuthorsLi, L. / Wen, Y. / Wrapp, D. / Jeong, J. / Zhao, P. / Xiong, W. / Atkins, C.L. / Shan, Z. / Hui, D. / McLellan, J.S. ...Li, L. / Wen, Y. / Wrapp, D. / Jeong, J. / Zhao, P. / Xiong, W. / Atkins, C.L. / Shan, Z. / Hui, D. / McLellan, J.S. / Zhang, N. / Ju, C. / An, Z.
External linksAntib Ther / PubMed:36683763
MethodsX-ray diffraction
Resolution3.3 Å
Structure data

PDB-8df1:
Chi3l1 bound by antibody C59
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Source
  • homo sapiens (human)
  • oryctolagus cuniculus (rabbit)
KeywordsIMMUNE SYSTEM / Chi3l1 / Fab / immunotherapeutic

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