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TitleStructural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 120, Page e2208941120-e2208941120, Year 2023
Publish dateApr 20, 2021 (structure data deposition date)
AuthorsPetrovic, S. / Roske, Y. / Rami, B. / Phan, M.H.Q. / Panakova, D. / Heinemann, U.
External linksProc. Natl. Acad. Sci. USA / PubMed:36656859
MethodsX-ray diffraction
Resolution1.819 - 2.995 Å
Structure data

PDB-7oas:
Structural basis for targeted p97 remodeling by ASPL as prerequisite for p97 trimethylation by METTL21D
Method: X-RAY DIFFRACTION / Resolution: 1.819 Å

PDB-7oat:
Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
Method: X-RAY DIFFRACTION / Resolution: 2.995 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

Source
  • arabidopsis thaliana (thale cress)
  • homo sapiens (human)
KeywordsTRANSFERASE / AtMETTL21D / lysine methylatransferase / Rossmann fold / AtCDC48 / p97 / AAA+ ATPase / ASPL / METTL21D / VCP-KMT / VCP / methylation / remodelling

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