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TitleA pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety.
Journal, issue, pagesJ Hematol Oncol, Vol. 16, Page 2-2, Year 2023
Publish dateJan 17, 2022 (structure data deposition date)
AuthorsLi, Y. / Liu, J. / Chen, W. / Wang, W. / Yang, F. / Liu, X. / Sheng, Y. / Du, K. / He, M. / Lyu, X. ...Li, Y. / Liu, J. / Chen, W. / Wang, W. / Yang, F. / Liu, X. / Sheng, Y. / Du, K. / He, M. / Lyu, X. / Li, H. / Zhao, L. / Wei, Z. / Wang, F. / Zheng, S. / Sui, J.
External linksJ Hematol Oncol / PubMed:36650558
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-7wn8:
Crystal structure of antibody (BC31M5) binds to CD47
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsANTITUMOR PROTEIN / Fab / human CD47 / Complex

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