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-Structure paper
Title | Allosteric inhibition of Staphylococcus aureus MenD by 1,4-dihydroxy naphthoic acid: a feedback inhibition mechanism of the menaquinone biosynthesis pathway. |
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Journal, issue, pages | Philos. Trans. R. Soc. Lond. B Biol. Sci., Vol. 378, Page 20220035-20220035, Year 2023 |
Publish date | Jan 14, 2022 (structure data deposition date) |
Authors | Stanborough, T. / Ho, N.A.T. / Bulloch, E.M.M. / Bashiri, G. / Dawes, S.S. / Akazong, E.W. / Titterington, J. / Allison, T.M. / Jiao, W. / Johnston, J.M. |
External links | Philos. Trans. R. Soc. Lond. B Biol. Sci. / PubMed:36633276 |
Methods | X-ray diffraction |
Resolution | 2.35 Å |
Structure data | PDB-7tin: |
Chemicals | ChemComp-TPP: ChemComp-GLY: ChemComp-CA: ChemComp-NA: ChemComp-CL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / Menaquinone biosynthesis / MenD / SEPHCHC Synthase |