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TitleThe homeodomain of Oct4 is a dimeric binder of methylated CpG elements.
Journal, issue, pagesNucleic Acids Res., Vol. 51, Page 1120-1138, Year 2023
Publish dateMay 10, 2022 (structure data deposition date)
AuthorsTan, D.S. / Cheung, S.L. / Gao, Y. / Weinbuch, M. / Hu, H. / Shi, L. / Ti, S.C. / Hutchins, A.P. / Cojocaru, V. / Jauch, R.
External linksNucleic Acids Res. / PubMed:36631980
MethodsX-ray diffraction
Resolution1.89 Å
Structure data

PDB-7xrc:
Crystal Structure of the dimeric Brn2 (Pou3f2) POU domain bound to palindromic MORE DNA
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus (mice)
  • synthetic construct (others)
KeywordsTRANSCRIPTION/DNA / POU family / TRANSCRIPTION-DNA COMPLEX

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