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Structure paper

TitleEvolution of nanobodies specific for BCL11A.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 120, Page e2218959120-e2218959120, Year 2023
Publish dateJul 26, 2022 (structure data deposition date)
AuthorsYin, M. / Izadi, M. / Tenglin, K. / Viennet, T. / Zhai, L. / Zheng, G. / Arthanari, H. / Dassama, L.M.K. / Orkin, S.H.
External linksProc. Natl. Acad. Sci. USA / PubMed:36626555
MethodsX-ray diffraction
Resolution2.199 - 2.447 Å
Structure data

PDB-8dtn:
The complex of nanobody 6101 with BCL11A ZF6
Method: X-RAY DIFFRACTION / Resolution: 2.199 Å

PDB-8dtu:
The complex of nanobody 5344N74D with BCL11A ZF6.
Method: X-RAY DIFFRACTION / Resolution: 2.447 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • lama glama (llama)
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / Nanobody / BCL11A / Transcription factor / Zinc finger domain / protein degradation / gamma globin / sickle cells

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