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TitleAutoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation.
Journal, issue, pagesCell Res., Vol. 33, Page 131-146, Year 2023
Publish dateJul 17, 2022 (structure data deposition date)
AuthorsDu, G. / Zhao, L. / Zheng, Y. / Belfetmi, A. / Cai, T. / Xu, B. / Heyninck, K. / Van Den Heede, K. / Buyse, M.A. / Fontana, P. ...Du, G. / Zhao, L. / Zheng, Y. / Belfetmi, A. / Cai, T. / Xu, B. / Heyninck, K. / Van Den Heede, K. / Buyse, M.A. / Fontana, P. / Bowman, M. / Lin, L.L. / Wu, H. / Chou, J.J.
External linksCell Res. / PubMed:36604598
MethodsNMR (solution)
Structure data

PDB-8dpx:
Preligand association structure of DR5
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / preligand association structure / autoinhibition state

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